Hippocampal excitability phase-locked to the theta rhythm in walking rats

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Abstract

Measures of monosynaptic activation of the CA1 and dentate regions of the hippocampus varied with the phase of the slow-wave theta rhythm in freely moving rats. Despite the fact that the theta rhythm recorded in CA1 is phase-reversed with respect to that recorded in the dentate region, peak excitability in both regions occurred about 110° after the positive peak of the dentate theta rhythm.

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    This work was supported in part by National Institutes of Health grant NS 14497 and National Science Foundation grant BNS 77-09375 to J. B. Ranck, and National Institutes of Health grant NS 10987 to V. E. Amassian.

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