Elsevier

NeuroImage

Volume 12, Issue 3, September 2000, Pages 276-286
NeuroImage

Regular Article
Neural Correlates of Episodic Retrieval Success

https://doi.org/10.1006/nimg.2000.0614Get rights and content

Abstract

Episodic memory retrieval involves multiple component processes, including those that occur when information is correctly remembered (retrieval success). The present study employed rapid-presentation event-related functional MRI that allowed different trial types with short intertrial intervals to be sorted such that the hemodynamic response associated with retrieval success could be extracted. Specifically, in an old/new episodic recognition task, hit trials (correctly recognized old items) and correct rejection trials (correctly rejected new items) were directly compared. The comparison revealed a mostly left-lateralized set of brain regions. Differential activation was most robust in left lateral parietal cortex and medial parietal cortex. Additional regions of differential activation included left anterior prefrontal cortex at or near Brodmann area 10, anterior insula, thalamus, anterior cingulate cortex, frontal cortex along inferior frontal gyrus, premotor cortex, and presupplementary motor area. These results suggest that left frontal and parietal regions modulate activity based on the successful retrieval of information from episodic memory. We discuss these findings in the context of several recent investigations that provide converging results as well as prior studies that have failed to detect these changes.

References (63)

  • S.F. Nolde et al.

    The role of prefrontal cortex during tests of episodic memory

    Trends Cognit. Sci.

    (1998)
  • M.D. Rugg et al.

    Retrieval processing and episodic memory

    Trends Cognit. Sci.

    (2000)
  • D.L. Schacter et al.

    Late onset of anterior prefrontal activity during true and false recognition: An event-related fMRI study

    NeuroImage

    (1997)
  • D.L. Schacter et al.

    Priming and the brain

    Neuron

    (1998)
  • E. Zarahn et al.

    Empirical analyses of BOLD fMRI statistics. I. Spatially unsmoothed data collected under null-hypothesis conditions

    NeuroImage

    (1997)
  • E. Zarahn et al.

    A trial-based experimental design for fMRI

    NeuroImage

    (1997)
  • N.C. Andreasen et al.

    Short-term and long-term verbal memory: A positron emission tomography study

    Proc. Natl. Acad. Sci. USA

    (1995)
  • J.R. Baker et al.

    Dynamic functional imaging of the complete human cortex using gradient-echo and asymmetric spin-echo echo-planar magnetic resonance imaging

    Proceedings of the Society of Magnetic Resonance First Scientific Meeting and Exhibition

    (1993)
  • P.A. Bandettini et al.

    Processing strategies for time-course data sets in functional MRI of the human brain

    Magn. Reson. Med.

    (1993)
  • G.M. Boynton et al.

    Linear systems analysis of functional magnetic resonance imaging in human V1

    J. Neurosci.

    (1996)
  • Braver, T. S, Barch, D. M, Kelley, W. M, Buckner, R. L, Raichle, M. E, Cohen, N. J, Miezin, F. M, Snyder, A. Z,...
  • R.L. Buckner

    Beyond HERA: Contributions of specific prefrontal brain areas to long-term memory retrieval

    Psychonomic Bull. Rev.

    (1996)
  • R.L. Buckner et al.

    Functional anatomical studies of explicit and implicit memory retrieval tasks

    J. Neurosci.

    (1995)
  • R.L. Buckner et al.

    Detection of cortical activation during averaged single trials of a cognitive task using functional magnetic resonance imaging

    Proc. Natl. Acad. Sci. USA

    (1996)
  • R.L. Buckner et al.

    Functional anatomic studies of memory retrieval for auditory words and visual pictures

    J. Neurosci.

    (1996)
  • R.L. Buckner et al.

    Encoding processes during retrieval tasks

    J. Cognit. Neurosci.

    (2000)
  • M.A. Burock et al.

    Randomized event-related experimental designs allow for extremely rapid presentation rates using functional MRI

    NeuroReport

    (1998)
  • V.P. Clark et al.

    fMRI study of face perception and memory using random stimulus sequences

    J. Neurophysiology

    (1998)
  • J.D. Cohen et al.

    An interactive graphic system for designing and controlling experiments in the psychology laboratory using Macintosh computers

    Behav. Res. Methods Instrument Comput.

    (1993)
  • A.M. Dale et al.

    Selective averaging of rapidly presented individual trials using fMRI

    Hum. Brain Mapp.

    (1997)
  • J.B. Demb et al.

    Semantic encoding and retrieval in the left inferior prefrontal cortex: A functional MRI study of task difficulty and process specificity

    J. Neurosci.

    (1995)
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