Table 2.

Summary of values from significant effects of cortical KCl at the 1.5-h time point compared to naive values

Treatment groupParameterValue
NaiveCortex, [14C]-sucrose RBR1.68 ± 0.32% weight
NaiveCortex, [3H] sumatriptan RBR2.50 ± 0.29% weight
NaiveBrainstem, [3H] sumatriptan RBR2.13 ± 0.35% weight
Postsurgical baselineFacial withdrawal threshold5.74 ± 0.47 g
Cortical KCl (1 M, 0.5 µl)Cortex, [14C] sucrose RBR3.12 ± 0.13% weight
Cortical KCl (1 M, 0.5 µl)Cortex, [3H] sumatriptan RBR3.76 ± 0.41% weight
Cortical KCl (1 M, 0.5 µl)Brainstem, [3H] sumatriptan RBR4.03 ± 0.25% weight
Cortical KCl (1 M, 0.5 µl)Facial withdrawal threshold0.96 ± 0.22 g
  • For reference, statistically significant BBB leak and facial allodynia were also observed in Figs. 1, 2.