Variable | Comparison | Data structure | Statistical test | Output | p value | Post hoc power | Effect size | |
---|---|---|---|---|---|---|---|---|
Marbles buried | pp | Celf6-Extended, genotype (Celf6+/+ vs Celf6+/- vs Celf) | Normal | Two-way ANOVA | F(2,117) = 6.209 | p = 0.03 | 0.886 | 0.326 |
Celf6-Extended, drug × genotype interaction | Normal | Two-way ANOVA | F(2,117) = 3.559 | p = 0.032 | 0.651 | 0.246 | ||
rr | Celf6 +/+ FLX vs vehicle | Normal | Simple main effect | F(1,117) = 14.687 | p = 0.0002 | 0.967 | 0.355 | |
ss | C57-Extended, drug (FLX vs vehicle) | Normal | One-way ANOVA | F(1,63) = 1.080 | p = 0.303 | 0.176 | 0.132 | |
tt | Long Prenatal, drug (FLX vs vehicle) | Normal | One-way ANOVA | F(1,42) = 1.456 | p = 0.234 | 0.218 | 0.188 | |
tt | Short Prenatal, drug (FLX vs vehicle) | Normal | One-way ANOVA | F(1,42) = 0.168 | p = 0.684 | 0.069 | 0.063 | |
Percent alternating trials | ww | Celf6-Extended, drug (FLX vs vehicle) | Non-normal | Two-way ANOVA | F(1,117) = 16.205 | p = 0.0001 | 0.979 | 0.373 |
ww | Celf6 +/+ FLX vs vehicle | Non-normal | Simple main effect | F(1,117) = 6.857 | p = 0.010 | 0.738 | 0.241 | |
ww | Celf6 +/- FLX vs vehicle | Non-normal | Simple main effect | F(1,117) = 10.292 | p = 0.002 | 0.889 | 0.297 | |
uu | Celf6-Extended vehicle Celf6 +/+, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 3.231 | p = 0.001 | N/A | 0.55 | |
uu | Celf6-Extended vehicle Celf6 +/-, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 4.228 | p = 0.00002 | N/A | 0.81 | |
uu | Celf6-Extended vehicle Celf6 -/-, compared to 50% | Non-normal | One-spl Wilcoxon | Z = 3.470 | p = 0.0005 | N/A | 0.71 | |
xx | C57-Extended, drug (FLX vs vehicle) | Non-normal | Mann–Whitney U | U(31) = 67.5 | p = 0.032 | N/A | 0.15 | |
vv | C57-Extended, vehicle compared to 50% | Non-normal | One-spl Wilcoxon | Z = 2.958 | p = 0.003 | N/A | 0.55 | |
vv | C57-Extended, FLX compared to 50% | Non-normal | One-spl Wilcoxon | Z = 0.608 | p = 0.543 | N/A | 0.03 | |
aaa | Long Prenatal, drug (FLX vs vehicle) | Non-normal | Mann–Whitney U | U(44) = 221.5 | p = 0.706 | N/A | <0.01 | |
eee | Long Prenatal, vehicle compared to 50% | Non-normal | One-spl Wilcoxon | Z = 2.303 | p = 0.021 | N/A | 0.22 | |
fff | Long Prenatal, FLX compared to 50% | Non-normal | One-spl Wilcoxon | Z = 1.608 | p = 0.108 | N/A | 0.14 | |
bbb | Short Prenatal, drug (FLX vs vehicle) | Normal | One-way ANOVA | F(1,40) = 1.555 | p = 0.220 | 0.229 | 0.196 | |
ggg | Short Prenatal, vehicle compared to 50% | Normal | One-sample t-test | t(19) = 3.324 | p = 0.004 | 0.883 | 0.743 | |
ggg | Short Prenatal, FLX compared to 50% | Normal | One-sample t-test | t(21) = 2.541 | p = 0.019 | 0.679 | 0.542 | |
No. of non-alternation trials | yy | Celf6-Extended, drug (FLX vs vehicle) | Non-normal | Two-way ANOVA | F(1,117) = 16.290 | p = 0.0001 | 0.979 | 0.373 |
yy | Celf6 +/+ FLX vs vehicle | Non-normal | Simple main effect | F(1,117) = 6.893 | p = 0.010 | 0.740 | 0.244 | |
yy | Celf6 +/- FLX vs vehicle | Non-normal | Simple main effect | F(1,117) = 9.267 | p = 0.003 | 0.855 | 0.281 | |
zz | C57-Extended, drug (FLX vs vehicle) | Non-normal | Mann–Whitney U | U(31) = 72 | p = 0.054 | N/A | 0.13 | |
ccc | Long Prenatal, drug (FLX vs vehicle) | Non-normal | Mann–Whitney U | U(44) = 171.5 | p = 0.214 | N/A | 0.04 | |
ddd | Short Prenatal, drug (FLX vs vehicle) | Normal | One-way ANOVA | F(1,40) = 1.555 | p = 0.220 | 0.229 | 0.196 | |
Percent response trials | hhh | C57-Extended, drug × filament interaction | Non-normal | One-way rmANOVA | F(7,98) = 3.113 | p = 0.005 | 0.932 | 0.472 |
iii | 0.16 g filament FLX vs vehicle | Normal | Simple main effect | F(1,112) = 4.104 | p = 0.045 | 0.519 | 0.19 | |
iii | 0.4 g filament FLX vs vehicle | Normal | Simple main effect | F(1,112) = 13.053 | p = 0.0005 | 0.948 | 0.34 | |
iii | 0.6 g filament FLX vs vehicle | Normal | Simple main effect | F(1,112) = 13.357 | p = 0.0004 | 0.952 | 0.35 | |
jjj | C57-Extended AUC, drug (FLX vs vehicle) | Non-normal | Mann–Whitney U | U(16) = 15.5 | p = 0.096 | N/A | 0.19 |
Effect size for F tests reported as Cohen’s f (Cohen, 1988; interpretation: 0.01 = small; 0.25 = medium; 0.40 = large), for t tests as Cohen’s d (interpretation: 0.2 = small; 0.5 = medium; 0.8 = large) and for nonparametric tests reported as η2.