Effect of tyrosine administration on catecholamine metabolites in urineq,r,s,t,u,v,w
| Variable | Placebo | Tyrosine | |||
|---|---|---|---|---|---|
| (mmol/M kr) | T0 | T2 | T0 | T2 | p value |
| HVA | 2.80 (0.22) | 3.36 (0.30) | 2.74 (0.24) | 3.20 (0.25) | 0.43 |
| MOPEG | 1.08 (0.06) | 1.34 (0.06) | 1.14 (0.07) | 1.3 (0.07) | 0.097 |
| VMA | 1.75 (0.11) | 2.1 (0.12) | 1.75 (0.1) | 2.0 (0.12) | 0.006 |
| DOPAC | 1.21 (0.11) | 1.25 (0.13) | 1.10 (0.1) | 1.28 (0.12) | 0.013 |
Metabolite concentrations are expressed in mmol/mol creatinine, to correct for sample volume; p values reflect the interaction between drug and time from the ANOVA on tyrosine administration (tyrosine, placebo) and time (T0, T2). The effect of tyrosine on catecholamine metabolites did not interact with age.