Statistical analysis
| Location | Data structure | Type of test | Confidence interval (95%) |
|---|---|---|---|
| a | Normal distribution | t test | Passive vs. active latency: 189.8 to 284.3 |
| b | Normal distribution | One-way ANOVA, Tukey’s t test | Control vs. active coping orexin mRNA: 1.3 to 2093; passive vs. active coping orexin mRNA: 749.8 to 3180 |
| c | Normal distribution | Correlation | Latency vs. orexin mRNA: –0.8 to 0.0 |
| d | Normal distribution | One-way ANOVA, Tukey’s t test | Control vs. active coping orexin mRNA: 0.2 to 1.2; passive vs. active coping orexin mRNA: 0.1 to 1.2 |
| e | Normal distribution | Correlation | Latency vs. orexin mRNA: –0.8 to –0.0 |
| f | Normal distribution | One-way ANOVA, Tukey’s t test | Control vs. passive coping body weight: 5.6 to 19.5; control vs. active coping body weight: 0.2 to 13.8 |
| g | Normal distribution | Two-way ANOVA, Tukey’s t test | Vehicle-treated control vs. vehicle-treated passive coping orexin mRNA: –1157 to –73.81; vehicle-treated passive coping vs. vehicle-treated active coping orexin mRNA: 80.6 to 1002; vehicle-treated passive coping vs. CNO-treated passive coping orexin mRNA: –26.99 to 1057 |
| h | Normal distribution | Two-way ANOVA, Tukey’s t test | Vehicle-treated passive coping vs. vehicle-treated active coping interaction time: –101.5 to –0.6; vehicle-treated passive coping vs. CNO-treated passive coping interaction time: –116.6 to –8.6 |
| i | Normal distribution | Two-way ANOVA, Tukey’s t test | Vehicle-treated control vs. vehicle-treated passive coping % immobility: –26.4 to –3.9; vehicle-treated control vs. CNO-treated control % immobility: –25.7 to –5.6; vehicle-treated passive coping vs. CNO-treated passive coping % immobility: 0.6 to 23.7 |
| j | Normal distribution | Two-way ANOVA, Tukey’s t test | Vehicle-treated control vs. vehicle-treated passive coping % activity: 3.9 to 26.4; vehicle-treated control vs. CNO-treated control % activity: 5.6 to 25.6; vehicle-treated passive coping vs. CNO-treated passive coping % activity: –23.7 to –0.6 |
| k | Normal distribution | Two-way ANOVA, Tukey’s t test | Vehicle-treated control vs. vehicle-treated passive coping % swimming: 4.3 to 26.3; vehicle-treated control vs. CNO-treated control % swimming: 3.5 to 24.0 |
| l | Normal distribution | t test | Vehicle vs. CNO-treated social interaction time: –32.5 to 50.8 |
| m | Normal distribution | t test | Vehicle vs. CNO-treated social interaction latency: –24.8 to 38.8 |
| n | Normal distribution | t test | Vehicle vs. CNO-treated social interaction distance traveled: –38,305 to 63,114 |
| o | Normal distribution | t test | Vehicle vs. CNO-treated % immobility: –5.7 to 21.8 |
| p | Normal distribution | t test | Vehicle vs. CNO-treated % activity: –21.8 to 5.7 |
| q | Normal distribution | Two-way ANOVA, Tukey’s t test | Vehicle-treated control vs. vehicle-treated active coping orexin mRNA: –35.82 to 889.3; vehicle-treated passive coping vs. vehicle-treated active coping orexin mRNA: –121.5 to 846.1; vehicle-treated control vs. CNO-treated control orexin mRNA: 92.88 to 975.8; vehicle-treated passive coping vs. CNO-treated passive coping orexin mRNA: 123.8 to 1091 |