Amyloid deposits in cognitively normal E4 homozygotes contrasted with E4 noncarriers
| Peak locationa | ||||
|---|---|---|---|---|
| Structure | x | y | z | z-score |
| Putamen | 15 | 12 | 0 | 4.7 |
| Inferior occipital Brodmann area 18 | –35 | –85 | –5 | 4.6 |
| Putamen | –15 | 12 | –2 | 4.5 |
| Middle occipital Brodmann area 19 | –44 | –73 | –9 | 4.2 |
| Inferior temporal Brodmann area 20 | 55 | –37 | –18 | 4.1 |
| ACC Brodmann area 32 | –6 | 21 | 36 | 4.0 |
| ACC Brodmann area 32 | –8 | 23 | 45 | 4.0 |
| Middle frontal Brodmann area 8 | 28 | 26 | 47 | 4.0 |
| Brodmann area 9 | 28 | 41 | 29 | 3.9 |
| Inferior temporal Brodmann area 20 | 39 | –24 | –23 | 3.8 |
| Middle frontal Brodmann area 10 | 42 | 50 | 0 | 3.7 |
| Medial frontal Brodmann area 9 | –10 | 44 | 20 | 3.6 |
| Middle frontal Brodmann area 8 | –24 | 35 | 43 | 3.6 |
| Brodmann area 9 | –28 | 46 | 27 | 3.5 |
| Brodmann area 36 | –48 | –40 | –20 | 3.4 |
| Brodmann area 6 | –24 | 8 | 56 | 3.3 |
| Inferior temporal BA 20 | –46 | –10 | –27 | 3.3 |
| Inferior temporal BA 20 | –48 | –17 | –25 | 3.2 |
| Brodmann area 10 | –10 | 35 | –13 | 3.2 |
| Superior temporal Brodmann area 22 | 53 | 1 | –2 | 3.2 |
| Inferior temporal Brodmann area 20 | 35 | –1 | –34 | 3.1 |
| Premotor Brodmann area 6 | 28 | –13 | 58 | 3.1 |
| Middle temporal Brodmann area 21 | 62 | –19 | –7 | 3.1 |
Locations in Talairach (Talairach and Tournoux, 1988) coordinates (mm): +x, right; –x, left; +y, anterior; +z, superior. ACC, anterior cingulate cortex.