Mice homozygous for e18a-CaV2.2 and 18a-CaV2.2 were viable and fecund
| Cross (het X het) | Cacna1btm3(e18a)DiLi | Cacna1btm4(Δe18a)DiLi |
|---|---|---|
| Litters | 32 | 42 |
| Progeny | 259 | 322 |
| Progeny/litter | 8.1 | 7.7 |
| Homozygous | 60 | 82 |
| Heterozygous | 137 | 152 |
| Wild type | 61 | 88 |
| Homozygous dead at weaning | 1 | 1 |
| Ratio of progeny observed (mut/mut:wt/mut:wt/wt) | 0.9:2.2:1 | 0.9:1.7:1 |
| Ratio of progeny expected (mut/mut:wt/mut:wt/wt) | 1:2:1 | 1:2:1 |