PYR-PV+ cell network scenarios, currents
| Parameter gpyr (nS), σe (nS), gpyr-pv (nS), gpv-pyr (nS), cPYR,PV,cPV,PYR, ge,mean = 0 nS | EPSC to PYR cell (pA) | IPSC to PYR cell (pA) | E/I ratio (PYR cell) | EPSC to PV+ cell (pA) | IPSC to PV+ cell (pA) | E/I ratio (PV+ cell) | Scenario |
|---|---|---|---|---|---|---|---|
| = [0.084, 0.2, 3, 8.7, 0.4, 0.5] | 4 | 1500 | ≪ 1 | 700 | 1800 | < 1 | A |
| = [0.084, 0.2, 3, 8.7, 0.2, 0.5] | 4 | 1600 | ≪ 1 | 550 | 1300 | < 1 | A |
| = [0.084, 0.2, 3, 8.7, 0.04, 0.5] | 5 | 1500 | ≪ 1 | 350 | 550 | ≈ 1 | B |
| = [0.084, 0.2, 3, 8.7, 0.02, 0.5] | 7 | 730 | ≪ 1 | 300 | 275 | ≈ 1 | B |
| = [0.084, 0.2, 3, 8.7, 0.4, 0.3] | 4 | 2500 | ≪ 1 | 650 | 1950 | < 1 | A |
| = [0.084, 0.2, 3, 8.7, 0.4, 0.7] | 4 | 1150 | ≪ 1 | 740 | 1770 | < 1 | A |
| = [0.014, 0.6, 3, 8.7, 0.02, 0.3] | 1 | 410 | ≪ 1 | 340 | 200 | > 1 | B |
| = [0.094, 0.6, 3, 8.7, 0.02, 0.3] | 7 | 430 | ≪ 1 | 220 | 200 | ≈ 1 | B |
| = [0.084, 0.2, 0.5, 6, 0.4, 0.5] | 7 | 2000 | ≪ 1 | 480 | 2450 | < 1 | A |
| = [0.084, 0.2, 2, 6, 0.4, 0.5] | 4 | 2200 | ≪ 1 | 650 | 2000 | < 1 | A |
| = [0.084, 0.2, 5, 6, 0.4, 0.5] | 4 | 2700 | ≪ 1 | 870 | 1900 | < 1 | A |
The same examples as in Table 4 but now showing excitatory and inhibitory currents and the delineated scenarios