Table 4.

List of genes whose expression level is significantly altered by the Shu mutation.^{^a}

Gene symbol	Cytogenetic location	Fold change	p-value^b	Function^c
DptB	55F8	↑12.2	0.0343	Defense response (antibacterial peptide)
AttC	50A3	↑8.94	0.0471	Defense response (antibacterial peptide)
CecC	99E2	↑8.22	0.0423	Defense response (antibacterial peptide)
AttB	51C1	↑7.99	0.0170	Defense response (antibacterial peptide)
CG31809	36B2	↑6.57	0.0009	Steroid dehydrogenase activity
AttA	51C1	↑6.31	0.0172	Defense response (antibacterial peptide)
Ste12DOR	12D2	↑3.33	0.0342	Protein kinase CK2 activity
CecB	99E2	↑3.17	0.0159	Defense response (antibacterial peptide)
PGRP-SB1	73C1	↑2.78	0.0300	Defense response (peptidoglycan binding)
CG42807	50B2	↑2.31	0.0246	Unknown
CanA-14F	14F	↑2.21	0.0109	Protein serine/threonine phosphatase activity
CG32368	66A19	↑2.20	0.0028	Unknown
Ccp84Aa	84A	↑2.13	0.0008	Structural constituent of chitin-based cuticle
CG31272	86C5	↑2.04	0.0283	Transporter/lipase activity
CG9377	34B7	↓14.3	0.0488	Serine-type endopeptidase activity
CG31116	86F8	↓3.57	0.0163	Voltage-gated chloride channel activity
Nox	53B3	↓2.28	0.0176	Electron carrier activity; oxidoreductase activity

↵^aGenes that were detected on all three chips for either wild-type (Kasuya et al., 2009b) or Shu RNA samples and differentially regulated in Shu with a fold change >2 and P < 0.05. Gene ranking is based on amount of fold change. ^bDetermined by Welch’s t-test (see Materials and Methods). ^cBased on FlyBase.