Table 1.

List of proteins whose expression was increased specifically in the WT or in both WT and Y1472F-KI SNI mice.

Accession no.	Name	Isotope reagent 115/114				Isotope reagent 117/116
Accession no.	Name	Ratio	p	Lower CI	Upper CI	Ratio	p	Lower CI	Upper CI
Q68EF6	Brain-enriched guanylate kinase-associated protein	1.3*	0.045	1.011	1.798	1.1	0.258	0.880	1.463
P28652	Calcium/calmodulin-dependent protein kinase type II beta chain	1.2*	0.031	1.018	1.385	1.1	0.067	0.990	1.283
Q923T9	Calcium/calmodulin-dependent protein kinase type II gamma chain	1.2*	0.008	1.060	1.363	1.1	0.094	0.977	1.285
Q6P9K8	Caskin-1	1.6*	0.001	1.403	1.732	1.1	0.512	0.769	1.526
Q6PFD5	Disks large-associated protein 3	1.2*	0.039	1.009	1.344	1.1	0.124	0.974	1.211
P05064	Fructose-bisphosphate aldolase A	1.2*	0.011	1.046	1.317	1.1	0.364	0.920	1.230
P16858	Glyceraldehyde-3-phosphate dehydrogenase	1.3*	0.000	1.178	1.426	1.1	0.137	0.974	1.198
P20357	Microtubule-associated protein 2	1.194*	0.005	1.081	1.319	1.217	0.096	0.954	1.551
P24369	Peptidyl-prolyl cis-trans isomerase B	1.265*	0.036	1.067	1.500	0.912	0.806	0.022	38.176
P15331	Peripherin	1.210*	0.020	1.039	1.409	1.085	0.192	0.952	1.236
Q9QYX7	Protein piccolo	1.179*	0.010	1.046	1.328	1.173*	0.011	1.042	1.321
Q9EQZ6	Rap guanine nucleotide exchange factor 4	1.201*	0.003	1.087	1.326	1.042	0.464	0.922	1.177
F6SEU4	Ras GTPase-activating protein SynGAP	1.194*	0.016	1.037	1.373	1.225*	0.002	1.088	1.381
Q64332	Synapsin-2	1.4*	0.036	1.052	1.844	1.2	0.48	0.434	3.469
P42669	Transcriptional activator protein Pur-alpha	1.173*	0.001	1.090	1.262	0.873	0.028	0.777	0.981

The expression level of 13 proteins was specifically increased in the WT after SNI. Two proteins were increased in both WT and Y1472F-KI mice. Lower CI is the lower bound of the confidence interval for the average ratio; upper CI is the upper bound of the confidence interval for the average ratio. *Significant increase.