Table 1.

Peak-aligned pairwise comparisons (individual drug groups)

p-values (t test)	Core (control) vs. shell (control)				Core (control) vs. core (cocaine)				Shell (control) vs. shell (cocaine)
Peak [DA], µm	0. 1	0.2	0.4	0.8	0.1	0.2	0.4	0.8	0.1	0.2	0.4	0.8
Peak	0.87	0.02	0.97	0.32	0.03	0.001*	0.07	0.66	0.81	0.42	0.94	0.03
Frequency	0.007*	0.001*	0.54	0.91	0.04	0.28	0.10	0.85	0.03	0.20	0.43	0.34
AUC	0.02	0.05	0.001*	0.008*	0.06	0.12	0.11	0.09	0.10	0.52	0.88	0.24
Rise velocity	<0.0001*	<0.0001*	<0.0001*	0.004*	0.002*	<0.0001*	0.008*	0.07	0.0004*	0.06	0.06	0.07
Latency peak	<0.0001*	<0.0001*	<0.0001*	<0.0001*	0.27	<0.0001*	0.12	0.003*	<0.0001*	0.02	0.22	0.53
V_max	<0.0001*	<0.0001*	<0.0001*	0.01	0.0008*	<0.0001*	0.02	0.08	0.63	0.52	0.53	0.36
FWHH	<0.0001*	<0.0001*	<0.0001*	<0.0001*	0.28	<0.0001*	0.15	0.003*	<0.0001*	0.14	0.67	0.93
Slope (T20–T80)	<0.0001*	<0.0001*	0.52	0.80	0.84	0.05	0.98	0.98	0.41	0.37	0.21	0.009*
Baseline return	0.0002*	0.002*	0.60	0.63	0.84	0.83	0.56	0.34	0.87	0.23	0.34	0.35
T20 latency	<0.0001*	<0.0001*	<0.0001*	<0.0001*	0.16	<0.0001*	0.12	<0.0001*	<0.0001*	0.07	0.69	0.89
T80 latency	<0.0001*	<0.0001*	0.02	0.85	0.91	0.10	0.80	0.40	0.0006*	0.87	0.41	0.08

Significance (p-value) of pairwise t tests at each peak bin (low [<0.1 μm DA], medium-low [0.1–0.2 μm DA], medium-high [0.2–0.4 μm DA], and high [0.4–0.8 μm DA]) between core control and shell control (left), core control and core cocaine (middle), and shell control and shell cocaine (right). Bold italics: *p < 0.01 (significant after Bonferroni correction); italics only: p < 0.05 (not significant after Bonferroni correction).