Table 4.

Stimulation index–aligned pairwise comparisons (collapsed drug groups)

p-values (t test)	Core (control) vs. shell (control)				Core (control) vs. both cocaines				Shell (control) vs. both cocaines
Stimulation index	100	300	600	1200	100	300	600	1200	100	300	600	1200
Peak [DA]	0.002*	0.96	0.02	0.48	0.0008*	0.003*	0.0001*	0.0003*	0.36	0.37	0.41	0.07
Frequency	0.97	0.002*	0.46	1.00	0.06	0.36	0.90	0.26	0.21	0.54	0.55	0.36
AUC	0.01	0.98	0.21	0.45	0.02	0.03	0.007*	0.003*	0.51	0.44	0.31	0.02
Rise velocity	0.0006*	0.006*	0.0003*	<0.0001*	<0.0001*	<0.0001*	<0.0001*	<0.0001*	0.43	0.27	0.92	0.69
Latency peak	0.002*	<0.0001*	<0.0001*	<0.0001*	0.005*	0.002*	0.0005*	<0.0001*	0.92	0.52	0.33	0.10
V_max	0.002*	0.003*	<0.0001*	0.0003*	0.0002*	<0.0001*	<0.0001*	<0.0001*	0.07	0.55	0.79	0.30
FWHH	<0.0001*	<0.0001*	<0.0001*	<0.0001*	0.02	0.001*	<0.0001*	<0.0001*	0.42	0.74	0.79	0.02
Slope (T20–T80)	0.001*	0.81	0.004*	0.26	0.002*	0.006*	<0.0001*	0.001*	0.007*	0.59	0.70	0.21
Baseline return	0.26	0.74	0.96	0.91	0.99	0.30	0.60	0.39	0.25	0.28	0.74	0.03
T20 latency	<0.0001*	<0.0001*	<0.0001*	<0.0001*	0.0004*	0.0007*	<0.0001*	<0.0001*	0.09	0.70	0.60	0.0003*
T80 latency	0.006*	0.25	0.02	0.0004*	0.83	0.51	0.05	0.23	0.02	0.10	0.75	0.07

Significance (p-value) of pairwise t tests at each stimulation index bin (low [100–300], medium-low [300–600], medium-high [600–1200], and high [>1200]) between core control and shell control (left; repeated from Table 3), core control and average of both cocaine groups (core and shell; middle), and shell control average of both cocaine groups (core and shell; right). Bold italics: *p < 0.01 (significant after Bonferroni correction); italics only: p < 0.05 (not significant after Bonferroni correction).