Wild-type (saline) | Wild-type (LPS) | Atm−/− (saline) | Atm−/− (LPS) | |
Cyclin A | 3.75 ± 0.35 | 4.27 ± 1.08 | 11.83 ± 2.50 | 25.2 ± 2.73 ** |
Cyclin D1 | 0.33 ± 0.33 | 0.88 ± 0.06 | 1.66 ± 0.87 | 2.42 ± 1.53 |
γ-H2AX | 11.5 ± 2.27 | 6.21 ± 3.32 | 45.9 ± 11.61 | 49.6 ± 14.0 |
Cleaved caspase 3 | 8.68 ± 2.16 | 10.2 ± 3.47 | 15.2 ± 0.78 | 14.4 ± 0.31 |
HDAC4 | 5.76 ± 2.94 | 1.76 ± 1.36 | 11.8 ± 5.32 | 4.63 ± 1.89 |
↵** Plus bold font = p < 0.05 compared with the Atm−/− group injected with saline.