Table 3.

Brain regions showing significant resting-state functional connectivity patterns for the group effect, and group × pain catastrophizing interactions

Seed	Region	Clustersize	MNI coordinates			t value cluster	p value cluster	Partial corr CTL		Partial corr PAT
Seed	Region	Clustersize	x	y	z	t value cluster	p value cluster	r	p	r	p
PAT > CTL
L aINS	L Cuneus	1549	−10	−66	2	4.03	<0.001	−	−	−	−
aMCC	R Lingual	1307	12	−56	−8	4.39	<0.001	−	−	−	−
CTL > PAT
L PCC	L DLPFC	364	−52	16	28	4.98	0.004	−	−	−	−
	R DLPFC	590	54	10	26	3.96	<0.001	−	−	−	−
	R PPC	381	34	−62	44	4.09	<0.001	−	−	−	−
	R IFG	250	36	36	−6	3.54	0.014	−	−	−	−
	R ITG	281	60	−44	−22	5.37	0.010	−	−	−	−
	L S1	477	−32	−38	42	5.53	0.001	−	−	−	−
	R S1	425	44	−32	48	3.79	0.002	−	−	−	−
	R mPFC	198	2	30	46	3.87	0.025	−	−	−	−
PCS: PAT > CTL
L aINS	L Hippo.	161	−26	−18	−10	3.97	0.034	−0.59	0.014	0.63	0.009
	L SMA	135	−36	−14	62	3.76	0.050	−0.47	0.055	0.67	0.004
	L Thalamus	235	−12	−18	2	4.55	0.013	−0.51	0.036	0.70	0.003
	R Thalamus	190	12	−24	14	4.21	0.023	−0.77	0.001	0.63	0.008
L PCC	L DLPFC	215	−36	22	28	3.74	0.020	−0.30	0.250	0.76	0.001
	R DLPFC	212	38	22	28	4.15	0.021	−0.52	0.034	0.81	0.001
aMCC	L Precuneus	146	−14	−64	28	4.10	0.052	−0.45	0.069	0.63	0.008
	R Precuneus	307	8	−66	30	3.84	0.008	−0.34	0.177	0.66	0.006
PCS: CTL > PAT
L PCC	R Cerebellum	539	14	−56	−36	5.39	0.001	0.63	0.006	−0.78	<0.001
	R Cerebellum	187	36	−52	−44	5.00	0.028	0.63	0.007	−0.67	0.004
	R Cerebellum	159	24	−78	−26	3.68	0.041	0.70	0.002	−0.59	0.015
	L Cerebellum	297	−16	−70	−26	4.36	0.008	0.82	0.001	−0.44	0.091

Hippo., Hippocampus; corr, correlations; PPC, posterior parietal cortex; SMA, supplementary motor area; PAT, migraine patients; CTL, healthy controls. Other abbreviations are as defined in the text.