Previous size range measurements of mammalian synaptosomes
| Study | Method | Species/region | Synaptosome fraction | Mean diameter (±SEM) |
|---|---|---|---|---|
| Dunkley et al. (1986) | Electron microscopy | Rat/cortex | P2 Percoll fraction 3 | 515 ± 17 nm |
| Dunkley et al. (1986) | Electron microscopy | Rat/cortex | P2 Percoll fraction 4 | 568 ± 14 nm |
| Dunkley et al. (1986) | Electron microscopy | Rat/cortex | P2 Percoll fraction 5 | 539 ± 12 nm |
| Dunkley et al. (1988) | Electron microscopy | Rat/cortex | S1 Percoll fraction 1 | 320 ± 130 nm |
| Dunkley et al. (1988) | Electron microscopy | Rat/cortex | S1 Percoll fraction 2 | 460 ± 150 nm |
| Dunkley et al. (1988) | Electron microscopy | Rat/cortex | S1 Percoll fraction 3 | 550 ± 130 nm |
| Dunkley et al. (1988) | Electron microscopy | Rat/cortex | S1 Percoll fraction 4 | 640 ± 120 nm |
| Dunkley et al. (1988) | Electron microscopy | Rat/cortex | S1 Percoll fraction 5 | 630 ± 190 nm |
| Robinson et al. (1989) | Electron microscopy | Rat/striatum | S1 Percoll fraction 3 | 591 ± 9 nm |
| Robinson et al. (1989) | Electron microscopy | Rat/striatum | S1 Percoll fraction 4 | 905 ± 12 nm |
| Hollingsworth et al. (1985) | Electron microscopy | Guinea pig/cortex | Filtration synaptoneurosomes | 560 ± 15 nm |
| Hollingsworth et al. (1985) | Light microscopy | Guinea pig/cortex | Filtration synaptoneurosomes | ∼600 nm |
| Williams et al. (2009) | Phase contrast microscopy | Human/cortex | Filtration synaptoneurosomes | 300 ± 700 nm |
| Fernández-Busnadiego et al. (2013) | Cryo-electron tomography | Mouse/cortex | Percoll fraction 3 + 4 | 500 ± 1000 nm |