Table 2.

Summary detailing the number and litters of female offspring tested in each behavior task

Offspring included in behavior testing
Total numberPPICMORSociabilityOddity preferenceLocomotor activity
TreatmentRatsLittersRatsLittersRatsLittersRatsLittersRatsLittersRatsLitters
Saline361536152215221522151411
PolyI:C351635152415241524152013
Number of litters with n = 5 or fewer offspring included in PPI
Treatmentn = 5n = 4n = 3n = 2n = 1
Saline15108
PolyI:C10717
Number of litters with n = 1 or n = 2 offspring in CMOR, sociability, and oddity
Treatmentn = 2n = 1
Saline78
PolyI:C96
Number of litters with n = 1 or n = 2 offspring tested in MK-801-induced locomotor activity
Treatmentn = 2n = 1
Saline38
PolyI:C76
  • All female offspring from n = 31 litters completed PPI, while all other tasks included one or two offspring per litter. The unexpected death of one polyI:C rat with no female littermates reduced the number of litters tested to 15. Locomotor activity n was reduced due to some rats being diverted to concurrent research. The number of offspring per litter in each task is further summarized below. behavior scores for littermates were averaged for a single value per litter.