TY - JOUR T1 - Serotonin-Mediated Effects of Maternal Presence on Brain Activity in the Prefrontal Cortex of Pups: Implications for Maternal Neglect JF - eneuro JO - eNeuro DO - 10.1523/ENEURO.0309-18.2018 VL - 5 IS - 4 SP - ENEURO.0309-18.2018 AU - Rosalind S.E. Carney Y1 - 2018/07/01 UR - http://www.eneuro.org/content/5/4/ENEURO.0309-18.2018.abstract N2 - Highlighted Research Paper: Maternal Regulation of Pups’ Cortical Activity: Role of Serotonergic Signaling, by, Emmanuelle Courtiol, Donald A. Wilson, Relish Shah, Regina M. Sullivan, and Catia M. TeixeiraBrain development in infants and children is severely impacted when bonding and attachment interactions with a primary caregiver do not occur. Such neglect includes the failure to provide basic needs, whether it be supervision and care, food, or hygiene (Robinson et al., 2017). In 2014, 7.1 per thousand children in the United States were victims of neglect (Child Trends, 2016). The perinatal period of brain development is particularly susceptible to these environmental insults. Neglect during this time can result in immediate abnormalities such as decreased brain electrical activity, decreased brain metabolism, and inadequate formation of reciprocal pathways between brain regions (National Scientific Council on the Developing Child, 2012). In the long-term, perinatal neglect can manifest in heightened fear, stress, depression, addiction, and cognitive defects (Nelson et al., 2011; Cameron et al., 2017). To mitigate these adverse … ER -