Article Information
- Received August 3, 2018
- Revision received December 14, 2018
- Accepted December 14, 2018
- Published online January 28, 2019.
Author Information
- Georgia Dermentzaki1,4,^,
- Kristin A. Politi1,4,^,
- Lei Lu2,4,^,
- Vartika Mishra1,4,
- Eduardo J. Pérez-Torres1,4,
- Alexander A. Sosunov3,
- Guy M. McKhann II3,
- Francesco Lotti1,4,
- Neil A. Shneider2,4 and
- Serge Przedborski1,2,4
- 1Department of Pathology and Cell Biology, Columbia University, New York, NY 10032
- 2Department of Neurology, Columbia University, New York, NY 10032
- 3Department of Neurological Surgery, Columbia University, New York, NY 10032
- 4Center for Motor Neuron Biology and Disease, Columbia University, New York, NY 10032
- Correspondence should be addressed to Serge Przedborski at sp30{at}cumc.columbia.edu.
Author contributions
Author contributions: F.L., N.A.S., and S.P. designed research; G.D., K.A.P., L.L., V.M., E.J.P.-T., and A.A.S. performed research; G.M.M. contributed unpublished reagents/analytic tools; G.D., K.A.P., F.L., and S.P. analyzed data; G.D., K.A.P, F.L., N.A.S. and S.P. wrote the paper.
Disclosures
The authors declare no competing financial interests.
This work was supported by National Institute of Neurological Disorders and Stroke Grants NS099862, NS072428, and NS107442 (to S.P.), NS101966 (to E.J.P.-T.), NS101575 (to F.L.), and NS073776 (to L.L. and N.A.S.); the United States Department of Defense Award W81XWH-13-1-0416 (to S.P.); the Project-ALS/Columbia University Preclinical Core (F.L., N.A.S, and S.P.); Innovation Awards from the Thompson Family Foundation Initiative (S.P. and F.L.); the National Science Foundation Grant DGE 1644869 (to K.A.P.); the National Institutes of Health and National Center for Advancing Translational Sciences Grant TL1 TR000082-07 (to K.A.P.); the Medical Scientist Training Program GM007367 (to E.J.P.-T.); and the ALS Therapy Alliance (L.L. and N.A.S.).
↵^ G.D., K.A.P., and L.L. have equally contributed to this work.
Funding
HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS)
NS099862; NS107442; NS101966; NS101575; NS073776US Department of Defense Award
W81XWH-13-1-0416Project ALS/Columbia University Preclinical Core
Innovation Awards from the Thompson Family Foundation Initiative
National Science Foundation (NSF)
DGE 1644869National Institute of Health and National Center for Advancing Translational Sciences
TL1 TR000082-07Medical Scientist Training Program
GM007367ALS Therapy Alliance
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