Passive parameters | | | |
1 | Specific membrane resistance, kΩ.cm2 | Rm | 35 | 30 to 40 |
2 | Specific membrane conductance, μF/cm2 | Cm | 1 | 0.5 to 1.5 |
Na channel parameters | | | |
3 | Maximal conductance, S/cm2 | Na-g | 0.007 | 0.005 to 0.01 |
4 | Inactivation time constant, ms | Na-τh | 2.34 | 1.87 to 2.81 |
5 | Activation time constant, ms | Na-τm | 0.163 | 0.13 to 0.20 |
6 | Slow inactivation time constant, ms | Na-τs | 106.1 | 84.88 to 127.32 |
7 | V1/2 inactivation, mV | Na-Vh | –45 | –47 to –43 |
8 | V1/2 activation, mV | Na-Vm | –30 | –32 to –28 |
9 | V1/2 slow inactivation, mV | Na-Vs | –60 | –62 to –58 |
KDR channel parameters | | | |
10 | Maximal conductance, S/cm2 | DR-g | 0.003 | 0.001 to 0.005 |
11 | Activation time constant, ms | DR-τn | 222.9 | 111.45 to 445.8 |
12 | V1/2 activation, mV | DR-Vn | 13 | 10 to 15 |
KA channel parameters | | | |
13 | Maximal conductance, S/cm2 | A-g | 0.008 | 0.001 to 0.01 |
14 | Inactivation time constant, ms | A-τl | 2 | 1 to 4 |
15 | Activation time constant, ms | A-τn | 0.137 | 0.086 to 0.43 |
16 | V1/2 inactivation, mV | A-Vl | –56 | –60 to –50 |
17 | V1/2 activation, mV | A-Vn | 11 | 8 to 15 |
CaT channel parameters | | | |
18 | Maximal conductance, mS/cm2 | T-g | 0. 1 | 0.05 to 0. 2 |
19 | Inactivation time constant, ms | T-τh | 31.02 | 10.24 to 46.53 |
20 | Activation time constant, ms | T-τm | 0.858 | 0.43 to 1.72 |
21 | V1/2 inactivation, mV | T-Vh | –75 | –80 to –70 |
22 | V1/2 activation, mV | T-Vm | –28 | –25 to –15 |
HCN channel parameters | | | |
23 | Maximal conductance, mS/cm2 | h-g | 0.08 | 0.005 to 0.05 |
24 | Activation time constant, ms | h-τl | 28.5 | 20.52 to 71.25 |
25 | V1/2 activation, mV | h-Vl | –81 | –85 to –70 |
CaL channel parameters | | | |
26 | Maximal conductance, μS/cm2 | L-g | 100 | 50 to 200 |
27 | Activation time constant, ms | L-τm | 0.189 | 1.8 to 7.2 |
28 | V1/2 activation, mV | L-Va | –27.01 | –30 to –24 |
CaR channel parameters | | | |
29 | Maximal conductance, μS/cm2 | R-g | 100 | 50 to 200 |
30 | Inactivation time constant, ms | R-τh | 12.7 | 6.35 to 25.4 |
31 | Activation time constant, ms | R-τm | 0.221 | 0.11 to 0.442 |
32 | V1/2 inactivation, mV | R-Vh | –39 | –43 to –35 |
33 | V1/2 activation, mV | R-Vm | 3 | –2 to 7 |
SK channel parameters | | | |
34 | Ca1/2 activation, nm | SK-Ca | 140 | 110 to 180 |
35 | Maximal conductance, μS/cm2 | SK-g | 1 | 0.5 to 5 |
36 | Activation time constant, ms | SK-τ | 196.8 | 98.4 to 393.6 |
BK channel parameters | | | |
37 | Maximal conductance, μS/cm2 | BK-g | 1 | 0.5 to 5 |
38 | Slope of Ca activation (mm) | BK-k1 | 4.8 × 10−4 | 2.8 × 10−4 to 6.8 × 10−4 |
39 | Ca1/2 activation (nm) | BK-k2 | 0.13 | 0.08 to 0.18 |
40 | Activation time constant, ms | BK-τ | 8.04 | 4.04 to 16.08 |
KM channel parameters | | | |
41 | Maximal conductance, μS/cm2 | M-g | 1 | 0.5 to 5 |
42 | Activation time constant, ms | M-τ | 6662 | 3331 to 13323 |
43 | V1/2 activation, mV | M-V | –40 | –45 to –35 |
CaN channel parameters | | | |
44 | Maximal conductance, μS/cm2 | N-g | 100 | 50 to 200 |
45 | Inactivation time constant, ms | N-τh | 1555 | 777.5 to 3110 |
46 | Activation time constant, ms | N-τm | 0.942 | 0.471 to 1.884 |
47 | V1/2 inactivation, mV | N-Vh | 39 | 35 to 44 |
48 | V1/2 activation, mV | N-Vm | 19.88 | 15 to 24 |